研究成果

實(shí)驗(yàn)室在精神疾病與精神衛(wèi)生學(xué)領(lǐng)域取得一系列成果，近年來，承擔(dān)省級(jí)課題29項(xiàng)，市級(jí)和其他課題18項(xiàng)，涉及精神障礙流行病學(xué)調(diào)查（涉及普通人群精神障礙患病率調(diào)查、睡眠障礙患病率調(diào)查、早年應(yīng)激相關(guān)精神障礙調(diào)查等）、精神障礙發(fā)病機(jī)制研究（涉及遺傳學(xué)、神經(jīng)影像學(xué)、生物標(biāo)記物、動(dòng)物模型、認(rèn)知功能、機(jī)器學(xué)習(xí)等多學(xué)科方向）、精神障礙創(chuàng)新診療手段（涉及非藥物治療手段、睡眠監(jiān)測(cè)、中藥治療等）的探討；發(fā)表SCI論文6篇，科研獲獎(jiǎng)10余項(xiàng)。其中，多巴胺受體D2型與超高危及首發(fā)精神分裂癥人群的相關(guān)性研究榮獲保定市科技進(jìn)步獎(jiǎng)一等獎(jiǎng)；首發(fā)雙相I型障礙躁狂發(fā)作患者的隨訪研究榮獲保定市科技進(jìn)步獎(jiǎng)二等獎(jiǎng)；巴戟天寡糖膠囊聯(lián)合舍曲林治療抑郁癥的臨床研究榮獲保定市科技進(jìn)步獎(jiǎng)二等獎(jiǎng)等。

主要論文成果

1. Sun L, Li K, Zhang L, Zhang Y. Associations Between Self-Reported Sleep Disturbances and Cognitive Impairment: A Population-Based Cross-Sectional Study. Nat Sci Sleep. 2022 Feb 15;14:207-216. doi: 10.2147/NSS.S347658. PMID: 35210888; PMCID: PMC8857964.

2. Sun L, Li K, Zhang Y, Zhang L. Differentiating the associations between sleep quality and suicide behaviors: A population-based study in China. J Affect Disord. 2022 Jan 15;297:553-558. doi: 10.1016/j.jad.2021.10.126. Epub 2021 Oct 30. PMID: 34728292.

3. Sun L, Li K, Zhang Y, Zhang L. Sleep-related healthcare use prevalence among adults with insomnia symptoms in Hebei, China: a population-based cross-sectional study. BMJ Open. 2022 Aug 17;12(8):e057331. doi: 10.1136/bmjopen-2021-057331. PMID: 35977764; PMCID: PMC9389099.

4. Zhang YS, Rao WW, Zhang LL, Jia HX, Bi H, Wang HL, Balbuena L, Li KQ, Xiang YT. Incidence rate of schizophrenia after the Tangshan earthquake in China: a 44-year retrospective birth cohort study. Transl Psychiatry. 2022 Sep 6;12(1):365. doi: 10.1038/s41398-022-02125-3. PMID: 36068195; PMCID: PMC9448782.

5. Yang J, Fan J, Cheng A, Zhao W, Wu D, Cui W, Zhang Y, Liu X. Hemodynamic analysis of the frontal cortex using multi-task fNIRS in major depressive disorder. J Affect Disord. 2022 Oct 15;315:206-212. doi: 10.1016/j.jad.2022.08.001. Epub 2022 Aug 4. PMID: 35932939.

6. Wen M, Dong Z, Zhang L, Li B, Zhang Y, Li K. Depression and Cognitive Impairment: Current Understanding of Its Neurobiology and Diagnosis. Neuropsychiatr Dis Treat. 2022 Nov 29;18:2783-2794. doi: 10.2147/NDT.S383093. PMID: 36471744; PMCID: PMC9719265.

7. 劉力慧,李斯妮,程奧博等.抑郁癥患者自殺與血脂等因素相關(guān)性[J].中國(guó)健康心理學(xué)雜志,2022,30(06):820-825.

8. 王艷華,賈海玲,畢皓等.河北省老年人認(rèn)知功能與睡眠質(zhì)量關(guān)聯(lián)分析[J].中國(guó)神經(jīng)精神疾病雜志,2022,48(02):96-100.

9. 蔡淑君,史文佳,徐濤等.新冠肺炎治愈者的心理健康及睡眠質(zhì)量狀況調(diào)查[J].中國(guó)心理衛(wèi)生雜志,2022,36(06):539-544.